General Immunology Clinical Resources

Clinical Resources by Topic: Immunology

General Immunology Clinical Resources

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General Immunology Patient/Family Resources

Adkinson: Middleton: Allergy: Principles and Practice 6th Ed.-2003 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Section A - Immunology: Table of contents
Cummings: Otolaryngology: Head & Neck Surgery 4th Ed.-2005 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Part 1 - General Considerations in Head and Neck: Access document
  - Chapter 9 - Allergy and Immunology of the Upper Airway: Access document
    - Introduction: Access document
    - Innate and Adaptive Immunity: Access document
    - Self and Nonself: Access document
    - Cells of the Immune System: Access document
    - Lymphoid Organs: Access document
    - Antigen Presentation: Access document
    - Cell-Mediated Immune Responses: Access document
    - Humoral Immune Response: Access document
    - Innate Immune System: Access document
    - Immunopathology: Access document
    - Hygiene Hypothesis: Access document
    - Pathophysiology of Allergic Rhinitis: Access document
    - References: Access document
    - References: Access document
Hoffman: Hematology: Basic Principles and Practice 4th Ed.-2005 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Part II - Immunologic Basis of Hematology: Access document
  - Chapter 10 - Overview and Compartmentalization of the Immune System: Access document
    - Introduction: Access document
    - The Innate Immune System: Access document
    - Cells of the Innate and Adaptive Immune Systems: Access document
    - Anatomy of the Immune System: Access document
    - References: Access document
  - Chapter 11 - B-Cell Development: Access document
    - Introduction: Access document
    - The Hematopoietic Hierarchy and B-Lineage Commitment: Access document
    - Stages of Adult B-Cell Development: Access document
    - The Pro-B to Pre-B-Cell Transition: Access document
    - The Pre-B-Cell Receptor: Access document
    - The Pre-B to B-Cell Transition: Access document
    - Immunoglobulin Class Switching: Access document
    - The B-Cell Receptor: Access document
    - Generation and Selection of the Primary B-Cell Repertoire: Access document
    - Regulation of Primary B-Cell Development: Access document
    - Fetal B-Cell Development: Access document
    - Secondary Lymphoid Compartments: Access document
    - References: Access document
    - References: Access document
  - Chapter 12 - T-Cell and NK-Cell Immunity: Access document
    - Introduction: Access document
    - Antigen Recognition and T-Cell Development: Access document
    - Cellular Basis of the Immune Response: Access document
    - Natural Killer Cells: Access document
    - References: Access document
  - Chapter 13 - Dendritic Cell Biology: Access document
    - Introduction: Access document
    - Dendritic Cell Subsets and Development: Access document
    - The Concept of Maturation: Access document
    - Antigen Acquisition: Access document
    - Antigen Processing: Access document
    - T-Cell Activation: Access document
    - B-Cell Activation: Access document
    - NK-Cell Activation: Access document
    - Activation of Other Elements of the Immune System: Access document
    - Tolerance and Autoimmunity: Access document
    - Clinical Trials: Access document
    - Summary: Access document
    - References: Access document
  - Chapter 14 - Regulation of Activation of A and T Lymphocytes: Access document
    - Overview: Access document
    - B Lymphocytes: Access document
    - T Lymphocytes: Access document
    - References: Access document
    - References: Access document
  - Chapter 15 - Leukocyte Trafficking: Access document
    - Introduction: Access document
    - Entry Into Tissues: Access document
    - Positioning of Lymphocytes within Tissues: Access document
    - Exit From Tissues: Access document
    - Summary: Access document
    - References: Access document
  - Chapter 16 - Tolerance and Autoimmunity: Access document
    - Introduction: Access document
    - Self-Reactive Lymphocytes: Origin and Control: Access document
    - Breakdown of Self-Tolerance in Autoimmune Diseases: Access document
    - Implications and Therapy: Access document
    - References: Access document
- Part VI - Hematologic Malignancies: Access document
  - Chapter 85 - Atypical Immune Lymphoproliferations: Access document
    - Introduction: Access document
    - What Constitutes an Atypical Lymphoproliferation?: Access document
    - Virus-Associated Atypical Lymphoproliferations: Access document
    - Retroviruses And Lymphoproliferations: Access document
    - Drug-Associated Lymphoproliferations: Access document
    - Post-Transplant Lymphoproliferative Disorders: Access document
    - Atypical Lymphoproliferative Disease in Patients with Autoimmune Disorders: Access document
    - Genetically Linked Immunodeficiency and Lymphoproliferations: Access document
    - Atypical Lymphoproliferations of Unknown Cause: Access document
    - Conclusion: Access document
    - References: Access document
Chapter 9 - Cell-Mediated Immunity in Host Defense against Infectious Diseases: Access document
- Introduction: Access document
- Antigen Recognition: Access document
- Major Histocompatibility Antigens: Access document
- Antigen-Presenting Cells: Access document
- T Lymphocytes: Access document
- T-Cell Subsets: Access document
- Natural Killer Cells: Access document
- New Aspects of Cell-Mediated Immunity: Access document
- The Mucosal Immune System: Access document
- Transendothelial Migration: Access document
- Opportunistic Infections in Patients with Compromised Cellular Immunity: Access document
- Conclusions: Access document
Chapter 10 - Evaluation of the Patient with Suspected Immunodeficiency: Access document
- Introduction: Access document
- The Index of Suspicion: Access document
- Initial Evaluation: Access document
- Lymphocyte Immune Defects: Access document
- Phagocyte Immune Defects: Neutrophils: Access document
- Phagocyte and Lymphocyte Defects affecting Mononuclear Cells: Access document

Walsh: Campbell's Urology 8th Ed.-2002 (MD Consult): Table of contents - Medical Library subscription ( INFO )

Chapter 9 - Basic Principles of Immunology in Urology: Access document
- Innate and Acquired Immunity: Access document
- Phagocytosis: Access document
- Complement: Access document
- Lymphoid Organs and Tissues: Access document
- Immunoresponsive Cell Populations: Access document
- Cell Surface Activation: Access document
- Signal Transduction: Access document
- T Cell Activation And Effector Function: Access document
- Apoptosis--Programmed Cell Death: Access document
- Lymphocyte Tolerance: Access document
- Adhesion Molecules and Lymphocyte Trafficking: Access document
- Chemokines and Recruitment of Leukocytes: Access document
- Tumor Immunology: Access document
- Immunity to Infections: Access document
- Male Reproductive Immunology: Access document

Goldman: Cecil Textbook of Medicine 22nd Ed.-2004 (MD Consult): Table of contents - Medical Library subscription ( INFO )

Part VII - Principles of Immunology and Inflammation: Access document
- Chapter 41 - The Innate and Adaptive Immune Systems: Access document
  - General Principles of the Immune System: Access document
  - Leukocyte Migration and Homing: Access document
  - Innate Immune System: Access document
  - Adaptive Immune System: Access document
  - Suggested Readings: Access document
- Chapter 42 - The Major Histocompatibility Complex and Disease Susceptibility: Access document
  - Introduction: Access document
  - [The Major Histocompatibility Complex and Disease Susceptibility]: Access document
  - Suggested Readings: Access document
- Chapter 43 - Mechanisms of Immune-Mediated Tissue Injury: Access document
  - Introduction: Access document
  - [Mechanisms of Immune-Mediated Tissue Injury]: Access document
  - Suggested Readings: Access document
- Chapter 44 - Mechanisms of Inflammation and Tissue Repair: Access document
  - Introduction: Access document
  - [Mechanisms of Inflammation and Tissue Repair]: Access document
  - Suggested Readings: Access document
- Chapter 45 - Complement in Health and Disease: Access document
  - [Complement in Health and Disease]: Access document
  - Suggested Readings: Access document
Part XXI - Diseases of Allergy and Clinical Immunology: Access document
- Chapter 265 - Approach to the Patient with Allergic or Immunologic Disease: Access document
  - Introduction: Access document
  - Allergic: Access document
  - Immunologic Disease: Access document
  - Suggested Readings: Access document
- Chapter 266 - Diseases of the Thymus: Access document
  - [Diseases of the Thymus]: Access document
  - Suggested Readings: Access document
- Chapter 267 - Primary Immunodeficiency Diseases: Access document
  - Introduction: Access document
  - Approach to the Patient with Suspected Immune Deficiency: Access document
  - Selected Immune Defects: Access document
    - Defects of Antibody Production: Access document
    - Defects of the T-Cell System: Access document
    - Combined Defects: Access document
    - Diseases pf Cytolytic Pathways: Access document
    - Interferon-Γ-Associated Immune Deficiencies: Access document
    - Diseases Resulting from Abnormal Apoptosis: Access document
    - Phagocytic Defects: Access document
    - Other Immune Deficiencies: Access document
    - Complement Deficiencies: Access document
  - Tests Used to Investigate Immune Functions: Access document
  - Future Directions: Access document
  - Suggested Readings: Access document
Part V - Clinical Pharmacology: Access document
- Chapter 31 - Glucocorticosteroids in Relation to Inflammatory Disease: Access document
  - Introduction: Access document
  - Pharmacology: Access document
  - Clinical Use of Glucocorticosteroids: Access document
  - Grade A: Access document
  - Suggested Readings: Access document

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The Merck Manual 17th Ed.-1999: Table of contents

Chapter 146. Biology of the Immune System: Table of contents
- General: Access document
- T Cells and Cellular Immunity: Access document
- B Cells and Humoral Immunity: Access document
- The Complement System: Access document
- Resolution of an Immune Response: Access document
Chapter 147. Immunodeficiency Diseases: Table of contents
- General: Access document
- Primary and Secondary Immunodeficiencies: Access document
- Specific Immunodeficiencies: Access document

Pediatrics Resources See also General Pediatrics Resources

Long: Principles and Practice of Pediatric Infectious Diseases 2nd Ed.-2003 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Section N - Infections of the Fetus and Newborn: Access document
  - Chapter 96 - Immunologic Development and Susceptibility to Infection: Access document
    - Introduction: Access document
    - Phagocytic System: Access document
    - Natural Killer Cells: Access document
    - Complement: Access document
    - B Lymphocytes: Access document
    - T Lymphocytes: Access document
    - Summary of Pathogen-Specific Susceptibility: Access document
    - References: Access document
- Section S - Infections in Patients with Deficient Defenses: Access document
  - Chapter 107 - Evaluation of the Child with Suspected Immunodeficiency: Access document
    - Introduction: Access document
    - Identification: Access document
    - Management: Access document
    - References: Access document
  - Chapter 108 - Infectious Complications of Antibody Deficiency: Access document
    - Introduction: Access document
    - Transient Hypogammaglobulinemia of Infancy: Access document
    - Immaturity of Antigen Responsiveness: Access document
    - X-Linked Agammaglobulinemia: Access document
    - Immunodeficiency with Hyperimmunoglobulinemia M: Access document
    - Selective Immunoglobulin G Subclass Deficiencies with or without Immunoglobulin A Deficiency: Access document
    - Common Variable Immunodeficiency: Access document
    - Immunoglobulin A Deficiency: Access document
    - References: Access document
  - Chapter 109 - Infectious Complications of Complement Deficiencies: Access document
    - Introduction: Access document
    - Biochemistry and Biology of Complement: Access document
    - Role of Complement in Host Defense: Access document
    - Genetically Determined Deficiencies of Complement: Access document
    - Secondary Deficiencies of Complement: Access document
    - Diagnosis of Complement Deficiencies: Access document
    - Management: Access document
    - References: Access document
  - Chapter 110 - Infectious Complications of Dysfunction or Deficiency of Polymorphonuclear and Mononuclear Phagocytes: Access document
    - Introduction: Access document
    - Etiologic Agents: Access document
    - Pathologic Findings: Access document
    - Clinical Manifestations: Access document
    - Clinical Approach: Access document
    - Management: Access document
    - Complications: Access document
    - Prognosis and Sequelae: Access document
    - Recent Advances: Access document
    - Prevention: Access document
    - Specific Conditions: Access document
    - References: Access document
  - Chapter 111 - Infectious Complications of Cell-Mediated Immunity: Primary Immunodeficiencies: Access document
    - Introduction: Access document
    - Cell-Mediated Immunity and its Role in Control of Infection: Access document
    - Specific Disorders: Access document
    - References: Access document
  - Chapter 112 - Infectious Complications in Special Hosts: Access document
    - Sickle Hemoglobinopathy: Access document
    - Asplenia and Polysplenia: Access document
    - Renal Disease: Access document
    - Iron Overload States: Access document
    - Ciliary Dysfunction: Access document
    - Ascites: Access document
    - Cystic Fibrosis: Access document
    - References: Access document
Behrman: Nelson Textbook of Pediatrics 17th Ed.-2004 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Part 13 - The Immunologic System and Disorders
  - Section 1 - Evaluation of the Immune System
    - Chapter 112 - Evaluation of Suspected Immunodeficiency: Access document
  - Section 2 - The T-, B-, and NK-Cell Systems
    - Chapter 113 - T Lymphocytes, B Lymphocytes, and Natural Killer Cells: Access document
    - Chapter 114 - Primary Defects of Antibody Production: Access document
    - Chapter 115 - Primary Defects of Cellular Immunity: Access document
    - Chapter 116 - Primary Combined Antibody and Cellular Immunodeficiencies: Access document
  - Section 3 - The Phagocytic System
    - Chapter 117 - Neutrophils: Access document
    - Chapter 118 - Monocytes and Macrophages: Access document
    - Chapter 119 - Eosinophils: Access document
    - Chapter 120 - Disorders of Phagocyte Function: Access document
    - Chapter 121 - Leukopenia: Access document
    - Chapter 122 - Leukocytosis: Access document
  - Section 4 - The Complement System
    - Chapter 123 - The Complement System: Access document
    - Chapter 124 - Disorders of the Complement System: Access document
  - Section 5 - Hematopoietic Stem Cell Transplantation
    - Chapter 125 - Clinical Indications: Access document
    - Chapter 126 - Matching and Rejection: Access document
    - Chapter 127 - Graft Versus Host Disease (GVHD): Access document
    - Chapter 128 - Principles of Immunosuppression: Access document
    - Chapter 129 - Late Effects of Stem Cell Transplantation: Access document
Johns Hopkins: The Harriet Lane Handbook: A Manual for Pediatric House Officers 17th Ed-2005 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Part II - Diagnostic and Therapeutic Information: Access document
  - Chapter 14 - Immunology and Allergy: Access document
    - IV - Immunoglobulin Therapy: Access document
    - V - Evaluation of a Suspected Immunodeficiency: Access document
    - References: Access document

Geriatrics Resources See also General Geriatrics Resources

Merck Manual of Geriatrics: Table of contents
- Chapter 131. Aging and the Immune System: Access document
  - Introduction: Access document
  - Changes in Natural (Innate) Immunity: Access document
  - Changes in Adaptive (Acquired) Immunity: Access document
  - Changes in Mucosal Immunity: Access document
  - Changes in Allergic Reactivity: Access document
  - Clinical Effects of Immune Senescence: Access document

Pathology Resources

Kumar: Robbins and Cotran: Pathologic Basis of Disease 7th Ed.-2005 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Chapter 6 - Diseases of Immunity: Access document
  - General Features of the Immune System: Access document
  - Disorders of the Immune System: Access document
  - References: Access document
Henry: Clinical Diagnosis and Management by Laboratory Methods, 20th Ed.-2001 (MD Consult): Table of contents - Medical Library subscription ( INFO )
- Part IV - Hematology, Coagulation and Transfusion Medicine: Access document
  - Chapter 30 - Immunohematology: Access document
    - Basic Immunohematologic Concepts: Access document
    - Erythrocyte Antigens and Antibodies: Access document
    - Immunohematology Tests and Procedures: Access document
    - References: Access document
    - References: Access document
- Part V - Immunology and Immunopathology: Access document
  - Chapter 34 - Overview of the Immune System and Immunologic Disorders: Access document
    - Introduction: Access document
    - Lymphoid Cells: Access document
    - Nonlymphoid Cells: Access document
    - Humoral Factors: Access document
    - Histocompatibility Antigens: Access document
    - Mechanisms of Immunologic Injury: Access document
    - Laboratory Applications of Immunologic Assessment: Access document
    - References: Access document
  - Chapter 35 - Immunoassays and Immunochemistry: Access document
    - Immunoassays and Immunochemistry: Access document
    - Overview of General Principles of Immunoassays: Access document
    - Precipitin and Nephelometric Immunoassays: Access document
    - Particle Immunoassay: Access document
    - Radioimmunoassay: Access document
    - Enzyme Immunoassay: Access document
    - Fluorescent Immunoassay: Access document
    - Chemiluminescent Immunoassay: Access document
    - Instrument Automation and Modulation of Assay Systems: Access document
    - Rapid and Simple Test Devices for Point-of-Care Testing: Access document
    - References: Access document
  - Chapter 36 - Laboratory Evaluation of the Cellular Immune System: Access document
    - Introduction: Access document
    - Clinical Criteria for Evaluation of Cellular Immunity: Implications for Interpretation: Access document
    - Methodologic Approach to Cellular Immune Testing: Access document
    - Lymphocyte Proliferation as an In Vitro Method of Assessing Cellular Immunity: Access document
    - Granulocyte Function in Cell-Mediated Immunity: Access document
    - Methodology: Flow and Image Cytometry: Access document
    - Gating and Analysis: Access document
    - Quality Control and Quality Assurance in the Cellular Laboratory: Access document
    - References: Access document
  - Chapter 37 - Laboratory Evaluation of Immunoglobulin Function and Humoral Immunity: Access document
    - Introduction: Access document
    - Structural Properties of Antibodies: Access document
    - The Genetic Basis of Antibody Diversity: Access document
    - General Properties of Immunoglobulins: Access document
    - Clinical Significance of Immunoglobulins: Access document
    - Disease Diagnosis: Access document
    - References: Access document
  - Chapter 38 - Complement and Kinins: Mediators of Inflammation: Access document
    - Structure And Function of the Complement System: Access document
    - Genetic Complement Deficiencies: Access document
    - Assessment of Complement Activity in Disease: Access document
    - Complement in Disease States: Access document
    - Clinically Useful Complement Inhibitors: Access document
    - Assays of Complement: Access document
    - Kinins and the Kinin-Generating System: Access document
    - References: Access document
    - References: Access document
    - References: Access document
  - Chapter 39 - Cytokines and Adhesion Molecules: Access document
    - Cytokines: Access document
    - Cell Adhesion Molecules: Access document
    - Perspectives: Access document
    - References: Access document
  - Chapter 40 - Human Leukocyte Antigen: The Major Histocompatibility Complex of Man: Access document
    - Introduction: Access document
    - Genetics of the Major Histocompatibility Complex: Access document
    - Class I Molecules--HLA-A, -B, -C Subregions: Access document
    - Class II Molecules--HLA-DR, -DQ, -DP Subregions: Access document
    - Characteristics of Antigenic Fragments Bound by MHC Class I and Class II Molecules: Access document
    - Recognition of Foreign MHC Molecules: Access document
    - Tandem Repeats and Single Nucleotide Polymorphisms in the MHC: Access document
    - Minor Histocompatibility Molecules: Access document
    - HLA Nomenclature: Access document
    - Techniques for Identifying HLA Polymorphism: Access document
    - Tissue/Organ Transplantation: Access document
    - Summary: Access document
    - References: Access document
  - Chapter 41 - The Major Histocompatibility Complex and Disease: Access document
    - Introduction: Access document
    - Genes in the Non-HLA or Class III Region: Access document
    - Complotypes: Access document
    - Extended Haplotypes: Access document
    - Complement Typing: Access document
    - Role of MHC Class I and II Molecules as Immune Response Genes: Access document
    - MHC Disease Associations: Access document
    - Methods of Detecting Association or Linkage of Disease with Genetic Markers: Access document
    - Summary: Access document
    - References: Access document
  - Chapter 42 - Immunodeficiency Disorders: Access document
    - Introduction: Access document
    - Clinical Indicators of Immune Deficiency: Access document
    - Evaluation of the Immune System: Access document
    - First-Level Investigations: Access document
    - Second-Level Investigations: Access document
    - Third-Level Investigations: Access document
    - Summary: Access document
    - References: Access document
Internet Pathology Lab for Medical Education (FSU Coll of Med): Table of contents
- Immunopathology Index: Table of contents

Clinical Guidelines

MD Consult Practice Guidelines: Table of contents | Keyword search - Medical Library subscription ( INFO )
- Allergy, Asthma, and Immunology List of documents
National Guideline Clearinghouse: MeSH browse | Detailed search
- Immune System Diseases (MeSH browse): List of documents

Clinical Trials

ClinicalTrials.gov: Homepage
- Immune System Diseases: Table of contents
CenterWatch Clinical Trials Listing Service: Homepage
- Clinical Trials by Disease Categories: Table of contents
  - Immunology/Infectious Diseases: Table of contents
YAHOO - Health:Medicine:Clinical Trials
Additional Clinical Trials resources (These sites have not been reviewed.)

News Resources

Doctor's Guide to the Internet: Homepage
- Immunology News: List of documents
MD Consult: Homepage - Medical Library subscription ( INFO )
- Today in Medicine: Table of content (scroll down to Immunology)

Miscellaneous General Immunology Clinical Resources

HealthWeb: Homepage
- Immunology: Table of contents
  - Clinical Resources: List of documents
  - Communication: List of documents
  - Conferences & Events: List of documents
  - Consumer Health Resources: List of documents
  - Databases & Catalogs: List of documents
  - Educational Resources: List of documents
  - Evidence-Based Resources: List of documents
  - General Resources: List of documents
  - Meta Sites: List of documents
  - Online Publications: List of documents
  - Organizations: List of documents
  - Research Resources: List of documents
YAHOO - Health:Medicine:Immunology
Additional Immunology resources (These sites have not been reviewed.)

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